| Size: |
10 µg |
| |
|
| Product Overview: |
Recombinant mouse globular domain of adiponectin/acrp30 (amino acid residues, 111-247, gAcrp30) was overexpressed in E.coli and purified by using conventional chromatography techniques, 16 kDa (138 aa). |
| |
|
| Description: |
Adiponectin/Acrp30 (247amino acids) is adipocyte complement-related protein of 30 kDa and exclusively expressed in differentiated adipocytes. Adiponectin (Acrp30) is a member of the complement factor C1q family and consists of signal sequence, Non-homologous sequence, collagen domain and globular domain (gAcrp30). Adiponectin (Acrp30) expression is reduced in a variety of obese and insulin-resistant states in human, monkeys and mice. Injection of Acrp30 (247aa) or gAcrp30 (globular domain) lowers serum glucose and free fatty acid level in mice. |
| |
|
| Purity: |
>95% by SDS-PAGE. |
| |
|
| Formulation: |
Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 50 mM NaCl, 5 mM DTT, 10% glycerol. |
| |
|
| Storage: |
Can be stored at + 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or
-70°C. Avoid repeated freezing and thawing cycles. |
| |
|
| Gene Name: |
|
| |
|
| mRNA Refseq: |
|
| |
|
| Pathway: |
Adipocytokine signaling pathway; PPAR signaling pathway; Type II diabetes mellitus. |
| |
|
| Function: |
Hormone activity; protein binding; receptor binding. |
| |
|
| Synonyms: |
ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; AdipoQ; GBP28; adiponectin; apM-1; apM1; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; Gelatin-binding protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1Q and collagen domain-containing; adiponectin, C1Q and collagen domain containing; adipose most abundant gene transcript1; gelatin-binding protein 28; APN; 30kDa; adipo; adipocyte complement related protein; gAcrp30. |
| |
|