| Size: |
10 µg |
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| Product Overview: |
Recombinant human AK2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques, 28.6 kDa (259 aa). |
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| Description: |
Adenylate kinase (AK; adenosine triphosphate-adenosine monophosphate [ATP-AMP] phospho-transferase, EC 2.7.4.3) is a ubiquitous monomeric enzyme involved energy metabolism of prokaryotic and eukaryotic cells. Three isozymes (AK1, AK2 and AK3) are characterized in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. AK2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. |
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| Purity: |
>95% by SDS-PAGE. |
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| Formulation: |
Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 5 mM DTT, 20% glycerol. |
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| Storage: |
Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
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| Gene Name: |
| AK2 |
GeneID: 204 |
Chromosome Location: 1p34 |
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| mRNA Refseq: |
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| Pathway: |
Purine metabolism; Nucleotide metabolism. |
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| Function: |
ATP binding; adenylate kinase activity; nucleoside kinase activity; nucleotide binding; transferase Activity. |
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| Synonyms: |
ADK2; EC 2.7.4.3; AK 2; OTTHUMP00000004287; OTTHUMP00000004288; ATP-AMP transphosphorylase; ATP-AMP transphosphorylase 2; adenylate kinase 2; adenylate kinase isoenzyme 2, mitochondrial; adenylate kinase, mitochondrial. |