| Size: |
20 µg |
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| Product Overview: |
Recombinant human AKR1B10 protein was expressed in E.coli and purified by using conventional chromatography, 36 kDa (316 aa). |
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| Description: |
AKR1B10, also known as Aldo-keto reductase family 1, member B10, AKR1B10 is a monomeric protein that efficiently catalyzes the reduction of aromatic and aliphatic aldehydes and ketones. AKR1B10 is ubiquitously expressed in many human tissues but is highly expressed in small intestine, colon and adrenal gland. This protein is pathogenically involved in diabetic complications and has been reported that AKR1B10 is overexpressed in human tumors, such as liver, breast, and lung cancer, and may play a critical role in the development and progression of cancer. |
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| Purity: |
>95% by SDS-PAGE. |
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| Formulation: |
Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol. |
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| Specific Activity: |
Can be stored at + 4°C short term (1-2 weeks) For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
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| Gene Name: |
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| mRNA Refseq: |
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| Pathway: |
Ascorbate and aldarate metabolism; Bile acid biosynthesis; Bisphenol A degradation; Butanoate metabolism; Fructose and mannose metabolism; Galactose metabolism; Glycine, serine and threonine metabolism; Linoleic acid metabolism; Lysine degradation; Nucleotide sugars metabolism; Tetrachloroethene degradation. |
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| Function: |
Aldo-keto reductase activity; oxidoreductase activity; protein binding.
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| Synonyms: |
AKR1B10; aldo-keto reductase family 1, member B10 (aldose reductase); HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12; MGC14103; AKR1B10; EC 1.1.1.2; Aldo-keto reductase family 1 member B10; ARP; EC 1.1.1; ARP; aldo-keto reduct ase family 1, member B10; aldose reductase-like 1; small intestine reductase; aldose reductase-like peptide; aldose reductase-related protein; aldo-keto reductase family 1, member B11 (aldose reductase-like); Aldose reductase-like; SI reductase. |