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AGR2, His-tagged

Recombinant Protein, Human, Not Biologically Active

PRODUCT #: RP-444

 

Size: 20 µg
   
Product Overview: Recombinant human Anterior Gradient Homolog 2 fused to His-tag on N-terminal produced in E. coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (21-175) & having a molecular mass of 22 kDa.
   
Description: AGR2 (Anterior gradient 2 homolog) is the human orthologue of the secreted Xenopus laevis Anterior Gradient protein (XAG-2). This is a small, possibly secreted molecule of yet weakly defined functions that is widely expressed in human tissues. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor.
   
Purity: > 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
   
Formulation: The protein (1 mg/ml) contains 1X PBS pH-7.4.
   
Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
   
Gene Name:
 Anterior gradient homolog 2 GeneID:  10551 Chromosome Location:  7p21.3
   
mRNA Refseq:
  NM_006408         MIM:  606358 Protein Refseq:  NP_006399 UniProt ID:  O95994
   
Function: Protein binding.
   
Synonyms: AG2; GOB-4; HAG-2; XAG-2; PDIA17; AGR2; anterior gradient 2 homolog; secreted cement gland homolog; protein disulfide isomerase family A, member 17; Anterior gradient protein 2 homolog; hAG-2; AG-2; Secreted cement gland protein XAG-2 homolog; HPC8; UNQ515/PRO1030.
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS OR DIAGNOSTIC PROCEDURES.